Researchers studying how boosting w/ an mRNA vaccine impacted people primed by the ChAdOx1 vaccine report they had monoclonal antibodies w/ higher binding affinities & increased reactivity against viral variants, compared to those who were ChAdOx1-boosted.
We thank study nurse Ida-Lisa Persson and personnel at the Clinical Research Center at Umeå University Hospital for support, enrollment of study subjects, and sampling. We also thank Linnea Vikström, Maj Järner and Mikaela Lagerqvist at Umeå University for processing of samples and Alicia Edin, Umeå University Hospital for the summary of clinical data. We also acknowledge Parexel for assistance with figure preparation, and E. Krauland, J. Nett, and M.
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