Brain Activity of Bodily Symptoms in Anxiety Disorders

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Brain Activity of Bodily Symptoms in Anxiety Disorders
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Anxiety often manifests as physical symptoms in the body. Here's what to do about it, writes GrantHBrennerMD

Given their key role in anxiety and other conditions, it’s important to understand the potential relationship betweenby Yue Chen, Yue Wu, Jingjing Mu, Bensheng Qiu, Kai Wang and Yanghua Tian in the Journal of Affective Disorders sheds light on the relationship between anxiety and somatic complaints. with a reference group of 25 without diagnoses. The 33 GAD subjects were screened to ensure they did not have other psychiatric conditions.

Resting MRI scans were focused on fear circuits identified in prior research, using ALFF to detect significant findings correlating brain activity with and without somatic symptoms as a function of anxiety severity. Dysregulated hippocampal function is connected with obsessional thinking, behavioral inhibition, and abnormal consolidation of fear-related memories related to trauma. The hippocampus is thought to be involved in generalization of fear, as abnormal hippocampal function may fail to fence anxiety into specific circumstances.

Symptoms may result from impaired information processing in the thalamus. Weaker signals for the body, for example, may not get gated properly in the thalamus, leading to amplified perception of unpleasant sensations.

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