An FDA advisory committee recommended that Covid vaccine makers target two omicron subvariants — BA.4 and BA.5 — in new booster shots expected to come this fall.
That’s consistent with theBalloux said no difference has been observed so far between BA.4 or BA.5 symptoms and those of previous subvariants. But people who were infected with the original version of the omicron variant during the winter may be susceptible to the newer subvariants.Balloux added, though, that"BA.2, BA.4 and B.5 from a neutralizing antibody perspective are essentially interchangeable." That might mean that people who got BA.2 infections have some protection now.
"We have waning immunity now in the people who got boosted half a year or more ago," Montefiori said.The FDA estimates that omicron-specific boosters from Pfizer and Moderna will become available in"The companies are now scurrying to make the BA.4/BA.5-containing vaccine and test that clinically," Montefiori said.
"The virus is moving in a direction of escaping our vaccines more and more, but it has not found a way to escape the vaccines to a really significant degree," Montefiori said.
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