The project is titled “Evaluation of a specific LXR/PPAR agonist for treatment of Alzheimer’s disease.”
The Amin lab is developing a compound called AU403IS, which may help individuals with the APOe4 allele. This genetic variant may make certain people more susceptible to Alzheimer’s disease at an earlier age.
Activating LXR beta may help in regulating APOe4 in the brain. The research this grant supports helps to understand further how AU403IS can potentially be therapeutic for patients with the APOe4 allele and Alzheimer’s disease. Amin points out that graduate students are vital to the innovative work at the Harrison College of Pharmacy and across the Auburn campus.
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