Epicardial adipose tissue thickness is correlated with inflammation and fibrosis-related circulating biomarkers, cardiac concentric change, myocardial strain impairment, heart failure and overall cardiovascular disease risk, finds a study in BMCMedicine.
]. Current studies remain unclear as to the cardiovascular consequence and underlying mechanism of EAT thickening in the general population. The biochemical and myocardial relevancy of EAT and their contribution to the risk of adverse cardiovascular outcomes need to be explored.
The cardiac magnetic resonance which assessed EAT thickness was performed on participants in the offspring cohort during their examinations 7 and 8 in 2002 ~ 2006. The offspring cohort consisted of offspring of the original Framingham cohort and spouses of the offspring. The participants with CMR data and free of HF were included in this study. The investigation conforms with the principles outlined in the.
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