With vaccine authorization months away and schools in chaos now, families fret over how best to protect their children.
from the US Department of Health and Human Services, the rate of hospitalization went from 2.5 per 100,000 to more than 4 per 100,000 since mid-December, compared to a steady 0.6 per 100,000 in 5- to 11-year-olds.
The option of vaccinating the youngest kids won’t be available for a few months more. In December, Pfizer—the only manufacturer whose vaccine has been approved for children and teens—that the regimen tested in clinical trials for kids younger than 5 appeared inadequate. The initial two-dose regimen, each containing a tiny amount of antigen , produced an adequate immune response in children 6 to 23 months old but not in children 2 to 4 years old.
“I have actually been fielding a lot of calls from really desperate families who are at their wits’ end,” says Yvonne Maldonado, a pediatrician and professor of epidemiology and population health at the Stanford University School of Medicine, and principal investigator of the Pfizer vaccine trial there. “I don’t have great answers. It’s frustrating and it is frightening.”
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