Ancient DNA traces origin of Black Death

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Ancient DNA traces origin of Black Death
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Genomes show that plague-causing bacteria found in Kyrgyzstan graves are direct ancestors of those that triggered the medieval pandemic.

, killing up to 60% of the populace in some places. Historical records suggest that the bubonic plague emerged from the east: Caffa, on the Crimean peninsula, experienced one of the earliest-recorded outbreaks of plague during a 1346 siege by the army of the Mongol Empire. The Caucasus and other locales in Central Asia have been put forward as potential epicentres.strains, hinting at an East Asian origin for the Black Death. “There were all kinds of hypotheses in the literature.

To determine whether the burials held any relevance to the later Black Death, Slavin worked with Krause to track down the remains from the Kyrgyz cemetery — which had been excavated in the 1880s and 1890s and moved to St Petersburg, Russia. The team, led by archaeogeneticist Maria Spyrou at the University of Tübingen, Germany, sequenced ancient DNA from seven people whose remains were recovered, discoveringY.

Other evidence puts the origins of the Black Death in this part of Central Asia. Among modern strains ofbacteria, those sampled from marmots and other rodents in Kyrgyzstan, Kazakhstan and Xinjiang in northwest China, surrounding the Tian Shan mountain range, were most closely related to the Kara-Djigach strain. “We can’t really say it’s that village or that valley, but it’s likely that region,” says Krause.

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