Nature research paper: A tissue-like neurotransmitter sensor for the brain and gut
, Scheme showing the chemical structures of the polymer precursors and the laser carbonization process., Layout showing the dimensions of the multichannel NeuroString electrodes for the sensing in the brain., Fabrication process of the NeuroString for brain neurochemical sensing. A polymer precursor solution containing a polyamic acid mixed with a metalloporphyrin was uniformly drop-casted as a film on a polyimide substrate.
A high laser power of 30 W was subsequently used to cut into the desired size and shape and isolate the individual electrode strings with width 90 µm. The electrode area is dip-coated in another elastomer solution to fully encapsulate the graphene electrodes. For implantation in the brain, the NeuroStrings were dip-coated in a pullulan solution and dried overnight to form a rigid coating. The tips of electrodes were cut by a razor blade to expose the cross sections of the graphene.
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