A ‘stealth’ Omicron subvariant is now spreading, worrying experts

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A ‘stealth’ Omicron subvariant is now spreading, worrying experts
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Cases of the Omicron variant are on the decline in U.S. and worldwide—but a different version of Omicron is now gaining traction. Here's what the science shows so far

than the differences between the original virus and the Alpha variant, the first variant of concern. “BA.2 shares over 30 mutations with BA.1, but it also has 28 unique mutations,” says Shay Fleishon, an evolutionary geneticist and advisor to the Central Virology Laboratory in Israel., evolving into distinct subvariants before BA.

1 was detected by a stroke of luck: A pair of mutations deleted two amino acids from its spike protein, making BA.1 easier to distinguish from Delta in rapid tests.that rely on time-consuming but highly accurate genetic techniques.Most of the differences between BA.2 and BA.1 are in the spike protein of the virus, which it uses to anchor to and infect human cells. BA.2 also has a large number of mutations in other parts of its viral sequence that are not well understood.

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