A programmable dressing activated by skin temperature, tested in rats, may help wounds heal faster. Learn more in ScienceAdvances:
). The average IODs of group EMSD-C were 0.24, 0.23 and 0.20 for EGF, TGF-β, and VEGF, respectively, which were higher than those of groups MD-C , ED-C , and BC-C . Obviously, the EGF, TGF-β, and VEGF expression of the EMSD-C group exhibited a statistically significant enhancement compared with those of the BC-C group.
In this work, we present an electromechanical synergistic system as an effective therapeutic strategy for accelerating linear and circular wound healing. The flexible and noninvasive EMSD could render appropriate contraction by a programmable SMA metamaterial triggered by skin temperature and strengthen the endogenous electric field via a patterned antibacterial EEF.
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