A novel approach for analyzing foodborne zoonotic E. coli GWtweets UMich UMNews UofMaryland foodborne zoonotic infection infections genetics ecoli
By Bhavana KunkalikarMar 29 2023Reviewed by Lily Ramsey, LLM In a recent study published in the One Health journal, researchers in the United States identified extraintestinal Escherichia coli infections using source-related mobile genetic elements.
However, a fundamental comprehension still needs to be improved related to the origination and transmission dynamics associated with causative E. coli strains, especially zoonotic types that originate from food animals and are acquired via food intake. Closing these knowledge gaps is essential to curb and prevent these prevalent infections.
Simultaneously, all human clinical E. coli isolates were collected from urinary and blood specimens at the Flagstaff Medical Center, the principal clinical laboratory covering Flagstaff and the surrounding area. An enrichment technique obtained a single E. coli isolate from each meat item. Using disk diffusion, the antimicrobial susceptibility of the meat isolates was evaluated. Using standard procedures, E. coli isolates from urine and blood were obtained in the clinical laboratory.
Forensics And Toxicology eBook Compilation of the top interviews, articles, and news in the last year. Download a free copy To study potential zoonotic transmissions of E. coli, the team constructed rooted phylogenies associated with 56 individual STs comprising four or more E. coli isolates from human and meat isolates. Even among isolates derived from the same sample type and ST, the derived phylogenies demonstrated high genetic variation among the E.
The team utilized a two-class Bayesian latent class model to detect human E. coli isolates derived from food animals via contaminated meat. The criterion for evaluating the model was congruence between its anticipated origin and the true sample type.
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