1st babies born in Britain using DNA from 3 people

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1st babies born in Britain using DNA from 3 people
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The world's first baby born using the technique was reported in the U.S. in 2016.

LONDON — Britain's fertility regulator on Wednesday confirmed the births of the U.K.'s first babies created using an experimental technique combining DNA from three people, an effort to prevent the children from inheriting rare genetic diseases.

The genetic defects can result in diseases such as muscular dystrophy, epilepsy, heart problems and intellectual disabilities. About one in 200 children in Britain is born with a mitochondrial disorder. To date, 32 patients have been authorized to receive such treatment. “Mitochondrial donation treatment offers families with severe inherited mitochondrial illness the possibility of a healthy child,” the U.K. fertility regulator said in a statement Wednesday. The agency said it was still “early days” but it hoped the scientists involved, at Newcastle University, would soon publish details of the treatment.

Others warn that tweaking the genetic code this way could be a slippery slope that eventually leads to designer babies for parents who not only want to avoid inherited diseases but to have taller, stronger, smarter or better-looking children. Scientists in Europe published research earlier this year that showed in some cases, the small number of abnormal mitochondria that are inevitably carried over from the mother's egg to the donor's can reproduce when the baby is in the uterus, which could ultimately lead to a genetic disease.

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